Hydrochloric Acid
Medchemexpress LLC ARD-2585 | 2757422-79-8 | 98.2% | 763.28 | 1 MG
ARD-2585 is an exceptionally potent and orally active PROTAC degrader of androgen receptor. It achieves DC50 values of 0.04-0.1 nM in the VCaP cell line with AR gene amplification and in the LNCaP cell line carrying an AR mutation. ARD-2585 (100 nM) is effective in reducing the AR protein level at the 3 and 24 hour time-points by 78% (p < 0.01) and 60% at the 6 hour time-point (p > 0.05).
- Achieves DC50 values of 0.04-0.1 nM in VCaP and LNCaP cell lines.
- Reduces AR protein level by 78% at 3 and 24 hour time-points (100 nM).
- Exhibits antiproliferative activity against human LNCaP cells (IC50: 16.2 nM).
- Exhibits antiproliferative activity against human VCaP cells (IC50: 1.5 nM).
Aqua Solutions Hydrochloric Acid 1.5 Normal NIST Traceable, Solution (4L)
Hydrochloric Acid 1.5 Normal NIST Traceable, Solution (4L)
LaMarKa Chemical Company Hydrochloric Acid 2.0N Phenolphthalein Endpoint, 4l
Hydrochloric Acid 2.0N Phenolphthalein Endpoint, 4l Cube
Medchemexpress LLC Procarbazine Hcl 10Mmx1Ml Solu | HY-13733-10MMX1ML
Procarbazine Hcl 10Mmx1Ml Solu
Medchemexpress LLC Ard-2585 | 2757422-79-8 | 98.19% | 763.28 | 25 MG
ARD-2585 is described as an exceptionally potent and orally active PROTAC degrader of the androgen receptor.
- Achieves DC50 values of 0.04-0.1 nM in the VCaP cell line with AR gene amplification and in the LNCaP cell line carrying an AR mutation.
- At 100 nM, ARD-2585 reduces AR protein level by 78% at 3 hours and 60% at 6 hours.
Aqua Solutions Hydrochloric Acid 0.2576 N Soln, NIST Traceable (10L)
Hydrochloric Acid 0.2576 N Soln, NIST Traceable (10L)
LaMarKa Chemical Company Hydrochloric Acid 0.01N BCG/MR/NaOH Endpoint, 1gal
Hydrochloric Acid 0.01N BCG/MR/NaOH Endpoint, 1lgal Plastic Jug
Electron Microscopy Sciences Hydrochloric Acid 2% 500 ML
Used in Prussian Blue Method for Hemosiderin, Lillie (1965); Highman (1962); Perls (1867). References are Perls, M., Virchow's Arch. F. Path. Anat., 39:42-48, 1867, Highman, B., Arch. Path., 33:937-938, 1942, Lillie, R.D., Histopathologic Technic & Practical Histochemistry, 3rd Ed., McGraw Hill, N.Y., 1965, and Clark, G., (ed.), Staining Procedures, 3rd Ed., Williams & Wilkins, Baltimore, p. 157, c. 1973.
Aqua Solutions Hydrochloric Acid 4 Molar (From Trace Metals HCl) Solution (500ML)
Hydrochloric Acid 4 Molar (From Trace Metals HCl) Solution (500ML)
Apexbio Technology LLC Vardenafil HCl Trihydrate 330808-88-3 100mg
Vardenafil HCl Trihydrate (CAS 330808-88-3) is the trihydrate salt form of vardenafil a potent and selective inhibitor of phosphodiesterase type 5 (PDE5) In enzymatic assays vardenafil demonstrates an IC50 of 0 7 nM for PDE5 exhibiting high selectivity over other phosphodiesterase isoforms with significantly higher IC50 values for PDE1 PDE2 PDE3 PDE4 and PDE6 Vardenafil enhances relaxation of human trabecular smooth muscle in response to sodium nitroprusside acetylcholine and electrical stimulation and increases cGMP concentrations in human corpus cavernosum tissue These properties establish its utility in studies addressing cGMP-mediated smooth muscle relaxation and PDE5-related pharmacology